Muhammad et Larry combine des séquences d'archives de 1980 inédites et des conversations conduites avec des specialistes de la boxe, des sommités et ceux présents au match qui a opposé en 1980 les anciens partenaires Mohamed Ali et Larry Holmes. Des entraînements aux séquences domestiques, alors que les adversaires se préparent au combat et que leur relation évolue...

Muhammad and Larry combines one-of-a-kind, never-before-seen archival footage from 1980 with newly-produced reflective conversations with boxing experts, luminaries, and those who were at the fight. Maysles intimately documented both Muhammad Ali and Larry Holmes, from sparring matches to private moments at home, as they prepared for their upcoming fight in 1980. Muhammad and Larry takes a closer look at the connection that evolved, inside and out of the ring, between these two amazing athletes.